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Lypo-Spheric vitamin C ensures maximum cellular uptake, maximum usability and maximum benefits

Research confirms the off-the-charts bioavailability of Lypo-Spheric™ Vitamin C

Bioavailability off the chartsStudies show that as dose size increases, the amount of vitamin C that actually enters the bloodstream decreases exponentially. (Groff, et al, 1995) More recently, a study testing the bioavailability of liposome-encapsulated vitamin C against that of traditional vitamin C supplements was published in a peer-reviewed journal. The researchers - using LivOn's Lypo-Spheric™ Vitamin C - found that LivOn's "smart" lyposomal nano-spheres® were able to deliver roughly twice the maximum amount of vitamin C to the blood previously thought possible with an oral supplement. (Hickey, et al, 2008)


What Thomas E. Levy, MD, JD, says about Lypo-Spheric™ Vitamin C

Primal Panacea Author

"Comparing the bioavailability of all other oral vitamin C delivery with your oral liposomal delivery is like comparing a squirt gun to a fire hose. Not only am I convinced that the efficacy of Lypo-Spheric™ Vitamin C far surpasses any traditional oral vitamin C supplement, but my recent personal experience with it suggests that it may sometimes be better than IV injection."


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LivOn Labs Frequently Asked Questions

All Lypo-Spheric products

Lypo-Spheric Vitamin C

Lypo-Spheric GSH



All Lypo-Spheric products


Q: Why don't the Lypo-Spheric™ products dissolve in water?

A: It is this very lack of solubility that makes liposomes impervious to stomach acids and bile salts. It also gives them quick and easy access into the bloodstream and enables them to slip across cell membranes as they quickly and safely transport nutrients to their intended destination.

Q: When is the best time to take Lypo-Spheric™ products?

A: While there is no exact time these products have to be taken, we recommend taking them in the morning and/or early afternoon. Taking the products too late in the evening may cause a burst of energy which could interfere with your normal sleep schedule. We also recommend that you take them on an empty stomach, a few minutes prior to a meal, to provide the maximum and quickest entrance into the bloodstream.

Q: Does LivOn Use Non-GMO Phospholipids from Soy Lecithin?

A: We source ingredients from all over the world so we can use high-potency, non-GMO ingredients from natural sources whenever possible. We now guarantee that our Lypo-Spheric™ Vitamin C, and Lypo-Spheric™ GSH and Lypo-Spheric™ R-ALA are 100% non-GMO. A new, reformulated 100% non-GMO version of Lypo-Spheric™ AGE Blocker™ will be available in June 2014.

Q: Is Sunflower Lecithin Safer than Soy Lecithin?

A: Most of the phytochemicals in soybeans are also found in sunflower kernels, the source of sunflower lecithin. Like soybeans, sunflower kernels are well known to have protease inhibitors, phytates (phytic acid), saponins, isoflavones, oxalates and more.[1]

We have not found any evidence that soy or sunflower lecithin is unsafe. Sunflower lecithin is a wonderful source of phospholipids; it is not going to contain the same amounts of phytochemicals as a whole sunflower kernel. The same applies to high-quality soy lecithin and purified phospholipids extracted from soy lecithin - neither are going to contain the same amounts of the phytochemicals found in raw soybeans.

[1] Dr. Katherine Phillips of the Virginia Polytechnic Institute and State University compiled a comprehensive paper that covers the range of phytochemicals found in sunflower kernels in her Final Report on the "Phytochemicals in Sunflower (Helianthus annuus)" from April 2000. This paper can be downloaded from the National Sunflower Association at http://www.sunflowernsa.com/seed/sunflower-kernels-in-bakery-foods/phytochemicals-in-sunflower-kernel/.

Q: Are the Lypo-Spheric™ products safe for pregnant and/or breastfeeding women?

A: While the Lypo-Spheric™ products contain nutrients that are vital to a healthy mother and baby, we recommend consulting with your healthcare practitioner before consuming any Lypo-Spheric™ supplements while pregnant or breastfeeding.

Q: Should I take the Lypo-Spheric™ products on an empty stomach?

A: We recommend you take the product on an empty stomach because it will enter the bloodstream faster, however the product may be taken with food or after a meal and it will still be fully absorbed by the body.
For those who are prone to low blood sugar levels, the Lypo-Spheric™ AGE Blocker™ should be taken just before a light snack or meal. Hypoglycemic substances, like caffeine, should be avoided.

Q: Can I mix Lypo-Spheric™ products in hot beverages like coffee or tea?

A: We do not recommend mixing any of the Lypo-Spheric™ products in hot beverages like coffee or tea. For best results, we recommend taking the product with a cool beverage.

Q: Will the sodium benzoate in the Lypo-Spheric™ AGE Blocker react with the Lypo-Spheric™ Vitamin C?

A: Sodium benzoate and vitamin C mixed directly together, such as in a soft drink, can result in a limited production of benzene. Increased benzene production does not occur in products which do not contain both benzoate AND ascorbic acid.1,2 Lypo-Spheric™ Vitamin C has no sodium benzoate in it and Lypo-Spheric™ AGE Blocker™ does not contain ascorbic acid, so there is no possibility of benzene formation when these products are taken separately.
Even if you take Lypo-Spheric™ AGE Blocker™ concurrent with Lypo-Spheric™ Vitamin C, the mechanism of benzene formation requires conditions not present in this scenario.³ In addition, the majority of the ascorbic acid in the Vitamin C is encapsulated by liposomes, which prevent direct contact with the sodium benzoate during the very short time required for the liposomes to pass through the stomach.⁴
If you have any fear about the possibility of benzene forming in your stomach, simply take the Lypo-Spheric™ Vitamin C by itself on an empty stomach and wait at least 20 minutes before ingesting any product that contains sodium benzoate. You may also want to avoid taking Lypo-Spheric™ AGE Blocker™ with any beverages containing ascorbic acid.

¹ Gardner, L.K. and Lawrence, G.D. Benzene Production from Decarboxylation of Benzoic Acid in the Presence of Ascorbic Acid and a Transition-Metal Catalyst. J Agric. Food Chem., 41(5): 693-695, 1993.
² Gerlach V (1909) VII. Summary of the results. In: Physiological activity of benzoic acid and sodium benzoate. Wiesbaden, Verlagvon Heinrich Staadt [cited in US FDA, 1972a].
³ Department of Health and Human Services. Summary of Information on Benzene Formation in Food Products. Memorandum, January 18, 1991 (available at:http://nyc.indymedia.org/en/2006/01/63228.html).
⁴ Oussi D, Mokrini A, Chamarro E, Esplugas S (1998) Photodegradation of benzoic acid in aqueous solutions. Environmental technology,19(9):955-960.

Q: How much Lypo-Spheric™ product can I take per day?

A: The recommended dosage of the Lypo-Spheric™ product is one packet, taken 1 to 2 times per day. We recommend that you consult your healthcare practitioner before taking dosages that are higher than the recommended dosage.

Please note the Lypo-Spheric™ products are not intended to prevent, cure or treat any specific health condition or disease. If you are experiencing a health problem and are looking for a healthcare practitioner that is experienced with advanced, alternative medicine, we recommend visiting http://www.acam.org or http://www.riordanclinic.org.

Q: What's the best way to take Lypo-Spheric™ products?

A: We've found that, for most people, the easiest way is to squeeze the contents of the packet into 1-2 ounces of water, swirl gently to make sure the liposomes are not sticking to the bottom or sides of the glass, and to drink the whole mixture in one swallow. For those who don't like the taste, substitute with 1-2 ounces of a cool fruit or vegetable juice, for water. The contents of the packet will not dissolve.

Q: Can I still use the product if it was outside in extremely cold or hot temperatures?

A: Yes! The Lypo-Spheric™ products are routinely tested for changes in consistency and ingredient concentration at -20°C/-4°F and 40°C/104°F. When stored at -20°C/-4°F, the active ingredients will remain effective for at least 2 months, but the integrity of the liposomes may be damaged when frozen for more than 2 months. When stored at 40°C/104°F, the active ingredients of each product will remain effective for 1-2 months.

Q: Why do you use preservatives in the Lypo-Spheric™ products?

A: Preservatives are used in our products to prevent the growth of harmful bacteria and mold. We use preservatives that are best suited for each formulation. We only use the minimum amount necessary to provide you with safe, effective products.

Q: Is there foil used in the Lypo-Spheric™ packaging?

A: The Lypo-Spheric™ packet is comprised of a silver material that is laminated with two layers of polyethylene to provide a barrier between the layer of foil and the liquid product. This barrier protects the product from potential leaching, and from oxygen and moisture. The packet material is compliant with FDA CFR Title 21, Sections 177.1520 (c) 2.2, 177.1630 and 178.3910 for direct contact with all food types.

Q: Are the Lypo-Spheric™ products safe for children?

A: The Lypo-Spheric™ products are formulated for adults. Please consult your child's physician before giving your child any Lypo-Spheric™ product.

Q: Are the Lypo-Spheric™ products safe for pets?

A: The Lypo-Spheric™ products are formulated for humans. Some of our customers have chosen to supplement their pet's diet with the Lypo-Spheric™ Vitamin C and GSH, and have seen positive results. We recommend consulting with your veterinarian before starting any supplementation program for your pets.

Q: Should I consult my doctor before taking Lypo-Spheric™ products?

A: We recommend you consult with a healthcare professional before starting any diet, exercise or supplementation program, before taking any medication, or if you suspect you may have a health problem.
You should consult your doctor before starting a supplementation program that includes any form of vitamin C if you have hemochromatosis, any type of hemolytic anemia, G6PD deficiency, known kidney insufficiency or failure, or you are currently taking a blood thinner like warfarin (Coumadin).

Q: Are there any supplements or medications that should not be taken with Lypo-Spheric™ products?

A: The Lypo-Spheric™ products contain high-potency nutrients that should not interfere with other common dietary supplements when taken by a generally healthy person. If you are taking other dietary supplements under the direction of a physician, we recommend consulting your physician before adding Lypo-Spheric™ supplements to your regimen.

While the Lypo-Spheric™ products contain well-researched nutrients that are taken by millions of people around the world, it is possible they could interfere with certain medications. For example, vitamin C in any form can lessen the blood-thinning effects of Coumadin or Warfarin. We urge anybody on either of these medications to supplement vitamin C and any other antioxidants under the guidance of their physicians only, so that the desired prolongation of prothrombin time can be achieved over time.

If you are on prescription medication, we recommend you consult your healthcare professional or pharmacist before taking any Lypo-Spheric™ supplements. We also recommend you consult your healthcare practitioner before taking Lypo-Spheric™ R-ALA if you are taking glucose lowering medication, or receiving treatment for under-active or over-active thyroid.

Q: What makes Lypo-Spheric™ products unique?

A: Our Lypo-Spheric™ supplements are unique in three key ways:

  1. Each Lypo-Spheric™ product is formulated with one goal in mind: to provide you with effective doses of nutrients without the use of binders, fillers, artificial colors or artificial flavors.
  2. The nutrient-filled liposomes in each Lypo-Spheric™ product are small enough - and smart enough - to bypass the body's restrictive nutrient transport system, and quickly pass through the intestinal wall and into the bloodstream. Within minutes of taking a Lypo-Spheric™ product, millions of liposomes will start to move from your bloodstream and into your cells - intact, and ready to work.
  3. Our single-dose packaging protects the product from additional oxygen and moisture, which keeps your product fresh.


Q: How do I identify a "legitimate" liposome encapsulated supplement?

A: We have spent years researching the best formulation techniques and manufacturing processes for liposome encapsulated supplements. We work with some of the top liposome experts in the country, and they can evaluate the quality of a liposomal product through ingredient assays, particle size analyses, and liposome encapsulation efficiency tests. So as part of our ongoing research, we analyze every liposomal supplement we come across.

While we can't share the exact details of every liposomal product, we can give you guidance on some basic things to look for when determining the quality of a liposomal supplement. Read More...

Q: Can I blend the Lypo-Spheric™ products in a food processor or blender?

A: We do not recommend blending any of the Lypo-Spheric™ products in a food processor or blender.

Lypo-Spheric™ supplements are encapsulated in liposomes. Although these tiny bubbles are impervious to digestive juices and protect their valuable contents from oxidative degradation, they can be damaged with heat or violent agitation.

Q: Are there potential health risks associated with Phospholipids derived from soy?

A: Like many beans and grains, raw soybeans contain a variety of phytochemicals[1]. There is research on both sides of the soy debate showing that these phytochemicals provide a variety of health benefits, as well as potential health risks under certain conditions. The phytochemicals associated with potential health risks are often referred to as anti-nutrients.[2]

At LivOn Labs, we use highly purified phospholipids derived from soy lecithin. Virtually all of the anti-nutrients naturally found in soybeans, along with soy protein (which is of allergic concern to some individuals), are removed during the extraction process.

What remains is a high percentage of phospholipids like Phosphatidylcholine (PC), Phosphatidylethanolamine (PE) and Phosphatidylinositol (PI). The benefits of phospholipids found in lecithin have been well documented since the early 1900's, and they far outweigh any potential risk associated with the ingestion of miniscule amounts of anti-nutrients naturally found in soy lecithin.[3]

[1] As defined by the Linus Pauling Institute, phytochemicals are chemicals produced by plants that are generally thought to affect health, but are not essential nutrients.

[2] Anti-nutrients are natural or synthetic compounds that interfere with the absorption of nutrients.

[3] Kullenberg et al.: Health effects of dietary phospholipids. Lipids in Health and Disease 2012 11:3

Q: Is there any soy protein in the Lypo Spheric™ products?

A: We use Essential Phospholipids (EPL), which are made from soy lecithin. Virtually all of the soy protein, which is of allergic concern to some individuals, is removed from the EPL during the extraction process. While we cannot guarantee our products do not contain trace amounts of soy protein, we routinely conduct DNA testing on each product with an independent laboratory. To date, the laboratory has not been able to detect any amounts of soy protein in our products.

For more information on lecithin derived from soy, we recommend reading Secion II. C. of the FDA's Guidance on Food Labeling, which can be found at http://www.fda.gov.

Q: Can I take the Lypo Spheric™ products at the same time?

A: Yes, the Lypo-Spheric™ products can be taken at the same time.

Lypo-Spheric Vitamin C


Q: Will supplementing with vitamin C lead to the development of kidney stones?

A: Although some have theorized a correlation between vitamin C and the development of kidney stones, overwhelming evidence contradicts this hypothesis. Broad population studies suggest that those with the highest blood levels of vitamin C have the lowest incidence of kidney stones.

Q: Can I still use the Lypo-Spheric™ Vitamin C if the packets are puffy?

A: Yes! The packets may expand as latent air from the filling process tends to expand over time. This does not affect the quality of the product.

Lypo-Spheric GSH


Q: Where does GSH come from?

A: The body's cells make GSH from three amino acids - glutamate, l-cysteine and glycine, also referred to as "precursors." The body depends on the presence of these "precursors" and the cell's health status to make GSH. Since many of these precursors are missing from our modern diet and people frequently have less than healthy cells, natural GSH levels are often low.

Q: What does GSH stand for?

A: Glutathione Sulfhydryl

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